Critical Flaw Found in Lab Models of the Human Blood-Brain Barrier

This shows the outline of a body and a red brainHuman brain endothelial cells used to generate lab models of the human blood-brain barrier were missing several key proteins found in natural endothelial cells. The cells had more in common with epithelial, a type of cell not normally found in the brain. The findings put into question over a decade worth of lab-based research on the BBB.