Researchers have developed a new, non-invasive method to remove dysfunctional brain circuitry and surgically treat neurological conditions. The technique, called PING, uses focused ultrasound combined with microbubbles to penetrate the blood-brain barr…
Physical activity appears to reduce microglial activation and improve cognition in the aging human brain, researchers report.
A new framework reveals Alzheimer’s disease is far more complex than previously believed. Rather than being a disease where the same causes produce the same outcomes, researchers found three different models for the disease, each with its own character…
Findings suggest people with moderate Alzheimer’s disease perform better at daily tasks when surrounded by their usual clutter.
A class of drugs called BACE1 inhibitors, originally designed to treat Alzheimer’s disease, shows potential for the treatment of glioblastoma brain cancer.
White matter hyperintensities were more common in athletes who played more contact sports or had more head injuries and concussions during their sporting careers.
Study identifies a significant way in which a disrupted circadian clock drives inflammation in the body’s immune cells.
Switching to a diet that includes more leafy greens, including spinach and kale, reduces inflammation and oxidative stress, and improved symptoms associated with chronic migraine.
Amyloid-beta accumulation in the brain may contribute to deficits in circadian regulation of learning and memory during the early stages of Alzheimer’s disease.
A new brain model explored bursts of human brain activity never before studied. The bursts may serve as potential biomarkers for depression, dementia, schizophrenia, and ADHD.
The extracts of certain plants long used by Native Americans as topical analgesics activate the KCNQ2/3 potassium channel. The compounds provide pain relief and prevent diarrhea.
People who drink between 4 – 6 cups of coffee or tea per day have a lower risk of stroke and dementia, researchers report. Drinking coffee alone, or in combination with tea, was associated with lower risk of post-stroke dementia.
People with ALS have 2.5-fold higher levels of arachidonic acid, a lipid commonly found in fatty parts of meat and fish that spurs on inflammatory process, in their spinal motor cells than people without the disease. Treatment with caffeic acid, an ant…
A newly developed antibody-based treatment and protein-based vaccine reduced Alzheimer’s symptoms in mouse models, researchers report.
Harnessing the power of “dancing molecules”, researchers have developed a new injectable therapy that repairs tissue damage and reverses paralysis in mouse models. Within four weeks of receiving the injection, paralyzed mice regained the ability to walk.
Dasatinib, an FDA-approved drug for chronic myeloid leukemia, and an experimental drug for liver cancer reduced neuroinflammation, tau phosphorylation, and amyloid secretion in cell cultures of post-mortem brain samples of those with the APOE4 Alzheime…
Cholesterol synthesis in nerve cells ensures the replenishment of newly myelin-forming cells. The findings could provide new treatment options for the treatment of disorders associated with myelin loss, such as multiple sclerosis.
People who consume a diet containing anti-inflammatory foods, including fruits, vegetables, and coffee, are less likely to develop dementia as they age, a new study reports.
Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell’s mitochondria to fragment and increase oxidative stress. Red…
Repeatedly listening to personally meaningful music induced brain plasticity and improved cognitive function for patients with mild cognitive impairment and early-stage Alzheimer’s disease.