Article Correctness Is Author's Responsibility: Brain Gene Expression Patterns Altered by Chronic Opioid Use

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This shows the outline of a headOpioid use disorder affects genes associated with proinflammatory immune molecule encoding and genes associated with remodeling the extracellular matrix, suggesting the connection between neurons may be altered as a result of opioid use. Additionally, those with OUD have higher levels of microglia in the brain.